Degree of blood pressure control
Mean creatinine clearance (ml/ min/1.73
2
± SE)
P value
Baseline
5 years
Hypertensive patients
Intensive
75.0 ± 4.4
56.9 ± 5.8
0.035
Moderate
77.5 ± 5.5
52.6 ± 5.8
0.006
Normotensive patients
Intensive
84.5 ± 7.2
57.7 ± 9.2
0.032
Moderate
76.0 ± 6.3
52.9 ± 9.7
0.042
Table 1:
Effect of intensive versus moderate blood pressure control on the renal function of hypertensive and normotensive patients with overt diabetic nephropathy in the ABCD trial (57).