| Parameter (unit) |
normoalbuminuria (n = 27) |
microalbuminuria (n = 104) |
proteinuria (n = 130) |
ESRD (n = 48) |
P |
| Age (years) |
66 [61 - 72] |
68 [57 - 77] |
66 [58 - 75] |
69 [64 - 75] |
0.179 |
| Duration of diabetes (years) |
14 [10 - 22] |
8 [5 - 14] |
14.5 [8 - 20] |
17 [12 - 22] |
<0.001 |
| FPG (mmol/l) |
7.7 [6.2 - 10.2] |
7.9 [7.3 - 10.5] |
9.3 [7.5 - 11.3] |
7.8 [6.3 - 11] |
0.173 |
| HbA1C (%) |
6.4 [5.2 - 7.5] |
6.45 [5.35 - 8.1] |
8.1 [6 - 9.6] |
6.2 [5.2 - 7.8] |
0.062 |
| Total cholesterol (mmol/l) |
4.9 [4.3 - 6.3] |
4.9 [4.3 - 5.7] |
5.2 [4.3 - 6.2] |
4.8 [3.9 - 5.5] |
0.323 |
| Triglycerides(mmol/l) |
1.88 [1.32 - 2.97] |
2 [1.32 - 2.71] |
2.15 [1.52 - 3.52] |
2.11 [1.62 - 3.11] |
0.027 |
| Creatinin (µmol/l) |
90 [83 - 110] |
114 [92 - 147] |
139 [104 - 175] |
420 [250 - 550] |
<0.001 |
| Proteinuria (g/24h) |
0.11 [0.08 - 0.13] |
0.14 [0.08 - 0.22] |
1.33 [0.4 - 3.06] |
- |
<0.001 |
| GFR (ml/min per 1.73m2) |
1.62 [1.32 - 2.3] |
1.1 [0.7 - 1.6] |
0.88 [0.71 - 1.38] |
- |
<0.001 |
| UAE (mg/24h) |
10 [8 - 18] |
50 [21 - 160] |
181 [97 - 545] |
- |
<0.001 |
Data are expressed as median [interquartile range]. Comparisons were made by Kruskal-Wallis ANOVA.
Abbreviations: ESRD, end-stage renal disease; FPG, fasting plasma glucose; GFR, glomerular filtration rate; UAE, urinary albumin excretion. |
