All Black2 White
Population (N) 8221 1935 6286
Age 64.4 (54.8-71.0)1 61.2 (49.4-68.9) 65.1 (56.6-71.5)
Follow-up time in years 9.09 (6.43-13.12) 9.85 (6.8-14.3) 8.9 (6.3-12.7)
# of Creatinine Measures 20 (12-31) 25 (15-40) 19 (12-29)
# of Protein Measures 6 (3-12) 8 (4-14) 6 (3-11)
Average of first 12 mos. eGFR3 66.9 (57.3-77.8) 75.3 (62.3-88.7) 64.9 (56.6-74.5)
Average of last 12 mos. eGFR3 56.6 (43.8-67.6) 59.1 (42.2-72.7) 56.0 (44.1-66.3)
Protein Group 04 37.30% 22.40% 41.90%
ProteinGroup 15 32.70% 31.20% 33.20%
Protein Group 26 32.20% 46.40% 24.90%
RFL7 Group 08 -0.74 (-1.7, 0.27) -1.07 (-2.5, 0.17) -0.68 (-1.8, 0.28)
RFL Group 18 -0.95 (-2.10, 0.06) -1.13 (-2.5,0.7) -0.91 (2.0, 0.50)
RFL Group 28 -1.96 (-3.8, -0.46) -2.28 (-4.1, -0.75) -1.8 (-3.6, -0.35)
Died during study 33.30% 35.30% 32.70%
Ever eGFR<30 ml/min/1.73m2,9 23.20% 30.80% 21.00%
Ever eGFR<15 ml/min/1.73m2,10 8.00% 13.60% 6.30%
1. Median (interquartile range)
2. Black versus white characteristics for all=P <.001, except died during study=P <.04
3. Estimated GRF (eGFR) using 4 variable MDRD equation in ml/min/1.73 m2
4. Protein Group 0: all urinalysis protein results negative
5. Protein Group 1: urinalysis results trace to 1+ protein (30 mg/dL)
6. Protein Group 2: urinalysis results had at least one urinalysis result >2+ protein (100 mg/dL)
7. Renal function loss (RFL) change in eGFR per year
8. Median (interquartile range) for RFL in ml/min/1.73 m2/years, calculated as the difference in the average eGFR of the last 12 months minus the average of the first 12 months, divided by the years of follow up.
9. Had an eGFR < 30 ml/min/1.73 m2 at some point of the study
10. Had an eGFR <15 ml/min/1.73 m2 at some point in the study
Table 1: Subject Characteristics1