Table 2

	Black	White	Difference	P Value
Constant	104.10	92.80	11.40	<.001
eGFR 30³	-7.57	-7.80	0.23	NS
Died⁴	1.43	2.80	-0.75	NS
Log protein⁵	-3.00	-2.00	-1.00	<.001
Age⁶	-0.49	-0.49	0	NS
Male	5.90	5.90	0	NS
No eGFR 30 yrs⁷	-0.47	-0.17	-0.30	<.001
Yes eGFR 30 yrs⁸	-2.35	-1.75	-0.29	<.001

1. RFL-Renal function loss, rate of decline of MDRD eGFR in ml/min/1.73 m²/year
2. Reported coefficient and p values of mixed effects model
3. eGFR 30 defined as subpopulation who ever had eGFR< 30 ml/min/1.73 m² during study
4. Died during study
5. Log to base 10 converted urinalysis where trace=10, 1 ± 30, 2 ± 100, 3 ± 300, 4 ± 1000.
6. Age at entry
7. Interaction term of change in eGFR/year for patients who did not have eGFR < 30 ml/min/1.73 m² during the study. Values of coefficients are in ml/min/1.73 m²/yr. The coefficient for whites=-0.17, for blacks=-0.30+-0.47.
8. Interaction term of patients who ever had an eGFR < 30 during the study. Values of coefficients are in ml/min/1.73 m²/yr. The coefficient for whites who ever had eGFR < 30 ml/min/1.73 m² is -1.58+-0.17=-1.75, for blacks who ever had eGFR < 30 ml/min/1.73 m² is -1.75+-0.47 (black ever 30 years+years coefficients)=-2.35

Table 2: Mixed Effects Model of Black versus White RFL Differences^1,2