Figure 2: (A) Representative micrographs (x20) of PAS-D stained renal sections of sham and 24h-LPS treated animals. (B) Renal function assessed by measurement of urea levels (mmol/L) in plasma of WT (white bars), CD44s- (black bars) and CD44v3-transgenic mice (stacked bars). (C) Q-PCR analysis for KIM-1 and (D) NGAL gene expression. Values corrected for TBP transcript levels. (E) Quantification of tubular cell apoptosis rate by counting active caspase-3+ TEC per HPF (x40). Mean + SEM, n=7-8, *=p<0.05, #=p<0.05 vs sham