Figure 3: Renal inflammation. (A) Evaluation of lymphocyte influx by digital image analysis of CD3-stained paraffin renal sections from WT (white bars), CD44s- (black bars) and CD44v3-transgenic mice (stacked bars). Data expressed as percent positive area of the total areal analyzed. (B) Renal expression (pg/mg proteins) of MCP-1, (C) TNF-α, (D) IL-1β, (E) IL-10, (F) HGF and (G) TGF-β1. (H) Gene expression of A20, (I) IRAK-3, (J) SOCS-1 and (K) TLR4 in kidneys, assessed by Q-PCR assays. Values corrected for number of TBP transcripts. Data expressed as mean + SEM, n=7-8, *=p<0.05, #=p<0.05 vs sham.