Figure 1: Light microscopic findings. (a) Neither proliferative changes nor glomerular capillary wall abnormalities are observed. Mononuclear cell infiltration and periglomerular fibrosis are seen around the glomerulus. (b) Many granulomas, which are positive for fuchsine and varied in sizes, are diffusely seen in the interstitum. (c) Note that the giant granuloma is composed of non-caseating epitheloid (oval) and multinucleated giant cells (small arrows). Marked mononuclear cell infiltration is also observed around the granuloma. G: glomerulus. (a) and (c) Periodic acid-methenamine-silver stain, and (b) Elastica-Goldner stain. Original magnification: (a) ×200; (b) ×40; and (c) ×100.