Remission: |
Urine protein <4 mg/m2/h or nil/trace on Albustix for 3 consecutive early morning specimens. |
Relapse: |
Urine protein >40 mg/m2/h or Albustix 3+ or 4+ for 3 consecutive early morning specimens, having been in remission previously. |
Frequent relapses: |
Two or more relapses within 6 months of initial response or four or more relapses in any 12 months. |
Steroid dependence: |
Two consecutive relapses during corticosteroid therapy or within 14 d of its discontinuation. |
Steroid resistance: |
Absence of remission despite therapy with daily prednisolone at a dose of 2 mg/kg per day for 4 wk (in some institutions 3 methylprednisolone pulses are given in addition beofre steroid resistance is diagnosed). |
Early non responder: |
steroid resistance during the first episode. |
Late non responder: |
steroid resistance in a patient who had previously responded to corticosteroid therapyl |
Adapted with permission from: Sinha A, Bagga A. Nephrotic syndrome. Indian
Journal of Pediatrics 2012; 79(8): 1045-55