Immobilized ligand |
Analyte |
KD (nM) |
wta GPIbα |
wt VWF-A1 |
690 ± 3 nM |
|
p.Arg1306Gln VWF -A1 |
69 ± 0.2 nM |
p.Pro46Leu GPIbα |
wt VWF-A1 |
630 ± 2 nM |
|
p.Arg1306Gln VWF -A1 |
61 ± 0.4 nM |
p.Met255Val GPIbα |
wt VWF-A1 |
18 ± 0.09 nM |
|
p.Arg1306Gln VWF -A1 |
6 ± 0.05 nM |
awt stands for wild type |