S.No

Innovative strategy of DN toward self-sufficiency

A

By applying sensitive diagnostic markers such as CCr, FE Mg, renal hemodynamics to recognize early stage DN

B.

By implementing an appropriate therapeutic target to correct the renal ischemia

C.

By initiating the therapy at early stage DN associated with an adequate nitric oxide production

D

By treating with combined ACEI and ARB to enhance peritubular capillary flow and renal function

E

Collectively, this innovative strategy can effectively prevent the end-stage renal disease in DN