Patient characteristics

N

Overall

Phosphatemia

≤1.45 mmol/L (n=190)

>1.45 mmol/L (n=216)

P-value

Male sex (%)

406

61.0

64.7

57.4

0.131

Age, year (m ± SD)

406

68.2 ± 14.8

72.3 ± 12.1

64.5 ± 16.1

<0.001

Mode of dialysis initiation (%)

406

0.831

   Hemodialysis

86.7

86.3

87.0

   Peritoneal dialysis

13.3

13.7

13.0

Emergency first dialysis (%)

406

36.0

38.4

33.8

0.333

Body mass index, kg/m2 (m ± SD)

396

26.8 ± 5.5

26.0 ± 5.1

27.6 ± 5.7

0.003

Primary renal disease (%)

405

0.008

   Diabetic nephropathy

23.0

19.0

26.4

   Hypertensive nephropathy

23.5

29.1

18.5

   Glomerulonephritis

10.3

6.9

13.4

   Hereditary nephropathy

5.4

7.4

3.7

   Other/unknown

37.8

37.6

38.0

Comorbid conditions (%)

   Cardiovascular disease

406

60.1

64.7

56.0

0.073

   Diabetes mellitus

406

42.9

39.5

45.8

0.196

   Respiratory disease

406

14.8

15.8

13.9

0.590

   Active malignancy

406

4.7

5.8

3.7

0.321

   At least 2 comorbidities

406

47.3

51.6

43.5

0.105

   Hypertension

406

89.0 

90.5

87.5

0.332

Biological parameters (m ± SD)

   Proteinuria, g/24h

406

0.5 ± 0.5

0.5 ± 0.5

0.5 ± 0.5

0.652

   Hemoglobin, g/L

406

112.7 ± 13.7

114.1 ± 14.4

111.4 ± 12.9

0.048

   Serum calcium, mmol/L

401

2.2 ± 0.2

2.2 ± 0.2

2.1 ± 0.2

0.002

   Parathyroid hormone, ng/L

293

279.4 ± 270.5

237.0 ± 205.9

315.1 ± 311.0

0.014

   Serum bicarbonate, mmol/L

369

22.6 ± 3.7

22.9 ± 3.3

22.3 ± 3.9

0.119

   Albuminemia, g/L

320

35.2 ± 6.8

35.5 ± 6.7

34.8 ± 6.8

0.388

   Total cholesterol, mmol/L

324

3.6 ± 1.2

3.5 ± 0.9

3.7 ± 1.2

0.026

   Triglycerides, mmol/L

321

1.9 ± 1.1

1.8 ± 1.3

1.9 ± 1.0

0.561

   Last GFR, mL/min/1.73m2

406

17.6 ± 8.2

18.2 ± 7.5

17.0 ± 8.7

0.148

M ± SD = Mean ± Standard Deviation, GFR = Glomerular Filtration Rate
Table 1: Demographic, clinical and biological characteristics overall and according to serum phosphate level (N=406).