|
Graft Survival |
Patient Survival |
Variable |
Full |
Stepwise |
Full |
Stepwise |
BMI Category |
|
|
|
|
|
|
|
|
Underweight |
5.383 |
* |
6.159 |
** |
10.168 |
|
1.565 |
|
Normal |
Reference |
Reference |
Reference |
Reference |
Overweight |
2.283 |
* |
2.578 |
** |
1.002 |
|
0.942 |
|
Obese |
2.681 |
* |
2.846 |
** |
0.393 |
|
0.671 |
|
Morbidly Obese |
4.279 |
* |
4.351 |
** |
2.559 |
|
1.762 |
|
Extremely Morbidly Obese |
3.434 |
|
2.754 |
|
3.229 |
|
1.551 |
|
Recipient Characteristics |
|
|
|
|
|
|
|
|
Gender |
|
|
|
|
|
|
|
|
Female |
0.812 |
|
|
|
0.520 |
|
|
|
Race |
|
|
|
|
|
|
|
|
African American |
1.385 |
|
|
|
0.582 |
|
|
|
Other |
0.000 |
|
|
|
0.000 |
|
|
|
White |
Reference |
|
|
Reference |
|
|
Ethnicity |
|
|
|
|
|
|
|
|
Hispanic |
3.026E+06 |
|
|
|
1.726E+07 |
|
|
|
Age (years) |
|
|
|
|
|
|
|
|
18 - 30 |
Reference |
|
|
Reference |
|
|
31 - 44 |
2.993 |
|
|
|
9.893E+07 |
|
|
|
45 - 59 |
2.459 |
|
|
|
5.784E+07 |
|
|
|
> 60 |
3.613 |
|
|
|
5.141E+07 |
|
|
|
Primary cause of ESRD |
|
|
|
|
|
|
|
|
Diabetes mellitus |
2.227 |
|
|
|
47.176 |
|
|
|
Glomerulonephritis |
0.779 |
|
|
|
1.004 |
|
|
|
PKD |
1.798 |
|
|
|
4.130 |
|
|
|
Hypertension |
1.172 |
|
|
|
1.623 |
|
|
|
Unknown |
20.783 |
* |
|
|
0.000 |
|
|
|
Other |
Reference |
|
|
Reference |
|
|
Pre-Transplant Dialysis Duration |
|
|
|
|
|
|
|
|
None (pre-emptive) |
Reference |
|
|
Reference |
|
|
0-12 months |
1.691 |
|
|
|
14.737 |
* |
|
|
13-24 months |
1.906 |
|
|
|
20.687 |
* |
|
|
25-60 months |
1.784 |
|
|
|
13.530 |
|
|
|
More than 60 months |
2.325 |
|
|
|
31.123 |
* |
|
|
Diabetes |
0.402 |
|
|
|
0.028 |
|
|
|
PVD |
0.878 |
|
|
|
1.226 |
|
|
|
Donor Characteristics |
|
|
|
|
|
|
|
|
Gender |
|
|
|
|
|
|
|
|
Female |
1.855 |
|
|
|
1.069 |
|
|
|
Race |
|
|
|
|
|
|
|
|
African American |
0.965 |
|
|
|
0.088 |
|
|
|
Other |
0.652 |
|
|
|
0.229 |
|
|
|
White |
Reference |
|
|
Reference |
|
|
Age (years) |
|
|
|
|
|
|
|
|
≤ 18 |
2.052 |
|
|
|
0.915 |
|
|
|
19 - 30 |
Reference |
Reference |
Reference |
Reference |
31 - 44 |
0.571 |
|
0.482 |
* |
0.363 |
|
|
|
45 - 59 |
1.336 |
|
|
|
1.291 |
|
|
|
≥ 60 |
0.694 |
|
|
|
0.797 |
|
4.984 |
** |
BMI category (kg/m2) |
|
|
|
|
|
|
|
|
≥ 10 to < 25 |
Reference |
|
|
Reference |
|
|
≥ 25 to < 30 |
0.751 |
|
|
|
0.713 |
|
|
|
≥ 30 |
0.583 |
|
|
|
0.345 |
|
|
|
Death due to stroke |
2.405 |
* |
2.716 |
*** |
4.714 |
|
|
|
Terminal Creatinine ≥ 1.5 |
1.196 |
|
|
|
4.134 |
|
|
|
Hypertension history |
0.806 |
|
|
|
0.275 |
|
|
|
Diabetes |
1.864 |
|
|
|
32.789 |
|
|
|
CMV sero-positive |
4.087E+05 |
|
|
|
2.723E+06 |
|
|
|
Transplant Factors |
|
|
|
|
|
|
|
|
Donor type |
|
|
|
|
|
|
|
|
SCD |
Reference |
|
|
Reference |
|
|
ECD |
1.475 |
|
|
|
1.622 |
|
|
|
DCD |
0.549 |
|
|
|
0.265 |
|
|
|
Peak PRA % |
|
|
|
|
|
|
|
|
0-10% |
Reference |
|
|
|
|
|
|
11-30% |
0.531 |
|
|
|
0.000 |
|
|
|
>30% |
0.298 |
|
|
|
0.000 |
|
|
|
Unknown |
0.404 |
|
|
|
0.000 |
|
|
|
CMV sero-pairing |
|
|
|
|
|
|
|
|
Unknown |
0.000 |
|
|
|
0.000 |
|
|
|
Donor - / Recipient - |
Reference |
Reference |
Reference |
Reference |
Donor - / Recipient + |
0.000 |
|
1.949 |
* |
0.000 |
|
|
|
Donor + / Recipient - |
0.673 |
|
|
|
1.901 |
|
|
|
Donor + / Recipient + |
0.000 |
|
|
|
0.000 |
|
|
|
HLA Mismatches |
|
|
|
|
|
|
|
|
0 HLA mismatches |
Reference |
Reference |
Reference |
Reference |
1 HLA mismatches |
7.395 |
|
5.344 |
* |
0.010 |
|
|
|
2 HLA mismatches |
0.000 |
|
|
|
0.076 |
|
|
|
3 HLA mismatches |
1.925 |
|
|
|
2.253E+07 |
|
|
|
4 HLA mismatches |
1.387 |
|
|
|
5.460E+06 |
|
|
|
5 HLA mismatches |
1.880 |
|
|
|
1.660E+07 |
|
|
|
6 HLA mismatches |
3.451 |
|
|
|
9.818E+07 |
|
3.204 |
* |
Sensitized |
16.315 |
* |
4.564 |
*** |
1.445E+09 |
|
7.116 |
*** |
Cold Ischemia Time |
|
|
|
|
|
|
|
|
0 to < 15 hours |
Reference |
|
|
Reference |
|
|
15 to < 20 hours |
1.029 |
|
|
|
0.251 |
|
|
|
20 to < 26 hours |
0.888 |
|
|
|
0.154 |
|
|
|
26+ hours |
1.838 |
|
|
|
0.000 |
|
|
|
Unknown |
0.730 |
|
|
|
0.313 |
|
|
|
Year |
|
|
|
|
|
|
|
|
2000 |
Reference |
|
|
Reference |
|
|
2001 |
1.022 |
|
|
|
0.719 |
|
|
|
2002 |
0.719 |
|
|
|
0.219 |
|
|
|
2003 |
0.553 |
|
|
|
0.026 |
|
|
|
2004 |
0.688 |
|
|
|
0.074 |
|
|
|
2005 |
0.429 |
|
|
|
0.555 |
|
|
|
2006 |
1.352 |
|
|
|
1.764 |
|
|
|
2007 |
0.000 |
|
|
|
0.000 |
|
|
|
Length of Stay |
1.128 |
*** |
1.105 |
*** |
1.118 |
* |
1.085 |
* |
* P-value < 0.05
** P-value < 0.01
*** P-value < 0.001 |