Compounds

n.atoms

M.W

n.O,N

n.OH,NH

n.rot.b

mi.LogP

6a

14

190.202

4

3

2

1.056

6b

15

269.098

4

3

2

1.841

6d

25

403.232

6

2

5

3.353

6e

15

208.192

4

3

2

1.172

6f

15

208.192

4

3

2

0.223

6g

15

224.647

4

3

2

1.710

6h

16

220.228

5

3

3

1.089

6i

15

269.098

4

3

2

1.841

6j

16

283.125

4

3

2

2.063

11

14

255.115

3

3

2

2.336

15

22

364.219

5

3

3

3.861

16

24

392.229

6

2

3

3.489

Table 1: Molecular properties of the inhibitors.