Figure 1: Clusters based on 6,600 proteins and 65 normal tissues. The dendrograms shows how normal human cells fall into distinct categories using hierarchical clustering based on a correlation metric (A). The dendrograms shows that the cells in different tissues are arranged in groups that contain cells with similar functions. The different categories have been colour-coded according to CNS (light blue), hematopoietic system (green), mesenchymal cells (pink), squamous epithelia (yellow), endocrine cells (blue) and glandular and transitional epithelia (light and dark brown). The resulting dendrograms from the hierarchical clustering was confi rmed by additional unsupervised methods. In (B) a principal component analysis (PCA) was performed and in (C) a random forest distance calculation was applied followed by a multi dimensional scaling, represented in two dimensions.