Figure 2: Significantly expressed proteins in specific tissue groups. A student’s t-test was conducted to find significantly expressed proteins between the specific groups and all other tissues. The subset of proteins was used to calculate a PCA and a correlation metric based dendrograms in two dimensions. For the CNS group, 1836 proteins were found to be differentially expressed and the subset of differentially expressed proteins is used in a PCA and hierarchical clustering analysis (A). The group of CNS cells are clearly separated and within the CNS tissue group, there is a smaller separation between the neurological and non- neurological cells, 1371 proteins were differentially expressed in the hematopoietic lineage tissues, and this group of tissues is also separated from all other tissues in the PCA plot (B). Lung macrophages and bone marrow are two tissues that are a bit separated from the other tissues in the hematopoietic group. For the endocrine tissues (C) the group of cells show less homogeny and a larger spread between the cells within the endocrine group is obvious. The number of differentially expressed genes for the endocrine tissue group is 46. The tissues in the gastro-intestinal groups had 2800 differentially expressed proteins and cell types in this group show a low intrinsic spread and the cluster is clearly defined in the PCA plot (D). The tissues within the mesenchymal tissue group had 2536 differentially expressed proteins and within this group of cells, myocytes from striated muscle and heart form a distinct subgroup in the PCA plot (E). The squamous tissue group is distinct in the PCA plot were the number of differentially expressed genes was 581 (F). The most deviant cell type within the squamous group is surface epithelia of the tonsil. In the accompanying heat maps there is an even distribution between high and low protein expression in the significantly differentially expressed proteins except for the gastro-intestinal tract where all differentially expressed proteins are more highly expressed and the mesenchymal/endocrine class where almost every proteins is more lowly expressed than all other tissues.