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Figure 3: Pathways retrieved by DAVID in negative tests. 1,000 groups of 165 randomly-selected genes were submitted to DAVID. The X axis shows the number of pathways retrieved by DAVID and the Y axis shows the logarithm of the frequency of the tests (+ 1 to avoid log (0)). The total number of retrieved pathways is represented by the black dots for the negative tests and by the black star for the 165 genes of interest. The number of retrieved cancer pathways is represented by the red dots for the negative tests and by the red star for the 165 genes of interest. The number of retrieved pathways involved in proliferation and cell motility is represented by the green dots for the negative tests and by the green star for the 165 genes of interest. Finally, the number of retrieved pathways involved in pathogen recognition and phagocytosis is represented by the blue dots for the negative tests and by the blue star for the 165 genes of interest. |