S.no |
GeneSymbol |
Architecture/Domain |
Primary localization |
Alternate localization |
Biological process |
Molecular function |
Molecule class |
+/- |
Fold change
TBM/Normal |
1 |
CHI3L2 |
SP |
Nucleus |
N/A |
Bone remodeling |
Molecular function unknown |
Unclassified |
+ |
58 |
2 |
UBD |
UBQ |
Nucleus |
Cytoplasm |
Protein metabolism |
Ubiquitin-specific protease activity |
Ubiquitin proteasome system protein |
+ |
56 |
3 |
IGL@ |
IGC; IGV; SP |
N/A |
N/A |
Immune response |
Antigen binding |
Immunoglobulin |
+ |
42.5 |
4 |
IGHA2 |
Ig_LIKE; IGV; SP |
N/A |
N/A |
Immune response |
Antigen binding |
Immunoglobulin |
+ |
40 |
5 |
CXCL9 |
SCY; CC; CXC; SP |
Extracellular |
N/A |
Immune response |
Chemokine activity |
Chemokine |
+ |
36 |
6 |
IGHG1 |
Ig_LIKE; IGV |
N/A |
N/A |
Immune response |
Antigen binding |
Immunoglobulin |
+ |
32 |
7 |
SLAMF8 |
TM; SP |
Plasma membrane |
N/A |
Immune response |
Receptor activity |
Cell surface receptor |
+ |
24 |
8 |
GBP5 |
CC |
N/A |
N/A |
Cell communication; Signal transduction |
GTPase activity |
GTPase |
+ |
22 |
9 |
CARTPT |
SP |
Extracellular |
N/A |
Biological_
process unknown |
Molecular function unknown |
Unclassified |
+ |
20 |
10 |
CIITA |
LRR |
Nucleus |
N/A |
Immune response |
Transcription regulator activity |
Transcription regulatory protein |
+ |
20 |
11 |
LOC100131733 |
N/A |
N/A |
N/A |
N/A |
N/A |
N/A |
+ |
19 |
12 |
APOL6 |
TM; CC |
Cytoplasm |
N/A |
Metabolism; Energy pathways |
Transporter activity |
Transport/cargo protein |
+ |
18.5 |
13 |
CHI3L1 |
SP |
Extracellular |
N/A |
Cell growth and/or maintenance |
Extracellular matrix structural constituent |
Extracellular matrix protein |
+ |
16 |
14 |
IL4I1 |
SP |
N/A |
N/A |
Apoptosis; Immune response |
Catalytic activity |
Enzyme: Oxidase |
+ |
15 |
15 |
SERPINA3 |
SERPIN; SP |
Extracellular |
Cytoplasm; Nucleus |
Protein metabolism |
Protease inhibitor activity |
Protease inhibitor |
+ |
14 |
16 |
MYBPH |
FN3; IGC2 |
Cytoplasm |
N/A |
Cell growth and/or maintenance |
Structural molecule activity |
Structural protein |
+ |
14 |
17 |
SLAMF7 |
IG; TM; SP |
Plasma membrane |
N/A |
Immune response |
Receptor activity |
Cell surface receptor |
+ |
14 |
18 |
IL21R |
FN3; TM; SP; WSXWS |
Plasma membrane |
N/A |
Immune response |
Transmembrane receptor activity |
Cytokine receptor |
+ |
13 |
19 |
IDO1 |
N/A |
Cytoplasm |
N/A |
Metabolism; Energy pathways |
Catalytic activity |
Enzyme: Oxygenase |
+ |
13 |
20 |
SLC14A1 |
TM |
Plasma membrane |
N/A |
Transport |
Transporter activity |
Transport/cargo protein |
+ |
13 |
21 |
SCIN |
GEL |
Cytoplasm |
Plasma membrane |
Cell growth and/or maintenance |
Cytoskeletal protein binding |
Cytoskeletal associated protein |
+ |
11 |
22 |
PKD2L1 |
EF; TM; CC |
Plasma membrane |
N/A |
Transport |
Ion channel activity |
Ion channel |
+ |
11 |
23 |
CTAG1A |
N/A |
N/A |
N/A |
Biological_
process unknown |
Molecular function unknown |
Unclassified |
+ |
11 |
24 |
TYMP |
N/A |
Extracellular |
Cytoplasm; Nucleus |
Cell communication; Signal transduction |
Growth factor activity |
Growth factor |
+ |
11 |
25 |
LAX1 |
TM |
Integral to membrane |
N/A |
Cell communication; Signal transduction |
Receptor signaling complex scaffold activity |
Adapter molecule |
+ |
10 |
26 |
SPOCD1 |
TFS2M |
N/A |
N/A |
Biological_
process unknown |
Molecular function unknown |
Unclassified |
+ |
10 |
27 |
CD2 |
TM; SP |
Plasma membrane |
N/A |
Immune response |
Receptor activity |
Cell surface receptor |
+ |
10 |
28 |
TTR |
TRANSTHYR; SP |
Extracellular |
N/A |
Transport |
Transporter activity |
Transport/cargo protein |
- |
23 |
29 |
RELN |
EGF; SP |
Extracellular |
N/A |
Protein metabolism |
Serine-type peptidase activity |
Serine protease |
- |
19 |
30 |
LYVE1 |
LINK; TM; SP |
Plasma membrane |
N/A |
Cell communication; Signal transduction |
Receptor activity |
Cell surface receptor |
- |
19 |
31 |
DEFA3 |
SP |
Extracellular |
N/A |
Immune response |
Defense/immunity protein activity |
Defensin |
- |
15 |
32 |
HIAT1 |
TM |
N/A |
N/A |
Transport |
Transporter activity |
Transport/cargo protein |
- |
13 |
33 |
EXPH5 |
N/A |
Nucleus |
N/A |
Biological_
process unknown |
Molecular function unknown |
Unclassified |
- |
12 |
34 |
GLIPR1L2 |
SCP |
N/A |
N/A |
Biological_
process unknown |
Molecular function unknown |
Unclassified |
- |
12 |
35 |
TMED7-TICAM2 |
N/A |
N/A |
N/A |
- |
- |
- |
- |
12 |
36 |
ABHD3 |
SP |
N/A |
N/A |
Biological_
process unknown |
Molecular function unknown |
Unclassified |
- |
11 |
37 |
CNTN6 |
FN3; Ig_LIKE; IGC2; SP |
N/A |
N/A |
Cell communication; Signal transduction |
Cell adhesion molecule activity |
Adhesion molecule |
- |
11 |
38 |
C9orf5 |
TM |
N/A |
N/A |
Biological_
process unknown |
Molecular function unknown |
Integral membrane protein |
- |
11 |
39 |
EDNRB |
TM; SP |
Plasma membrane |
Lysosome; Endoplasmic reticulum |
Cell communication; Signal transduction |
G-protein coupled receptor activity |
G protein coupled receptor |
- |
11 |
40 |
TMCO3 |
TM; CC; SP |
Integral to membrane |
N/A |
Biological_
process unknown |
Molecular function unknown |
Integral membrane protein |
- |
10 |
41 |
APPBP2 |
CC |
Cytoplasm |
Cytoplasmic vesicle; Golgi apparatus |
Regulation of gene expression, epigenetic |
Molecular function unknown |
Adapter molecule |
- |
10 |
42 |
S100A12 |
N/A |
Cytoplasm |
N/A |
Cell communication; Signal transduction |
Calcium ion binding |
Calcium binding protein |
- |
10 |
