|
Resource |
Purpose |
Contents (Oct 2011) |
Data (Oct 2011) |
Limitation |
|
SEDB |
The SEDB describes the 3D-structure of epitope containing proteins and its interaction with protein. It also summarizes the source information, experimental details and additional related information of epitope such as methodology and detailed sequence information along with user convenient Jmol tool for epitope visualization.
URL: http://sedb.bicpu.edu.in |
It contains all the structure of TCR, MHC, and BCR complexes available in PDB, with emphasis on the structural characterization of these complexes. Additionally, It also includes Ramachandran Plot, DIMPLOT, and Methodology and Gene Ontology information. Reference in details and the Assay information. It complements other existing specialized 3D epitope databases. |
B-Cell - 271
T-Cell - 49
MHC - 299
Extracted from the Protein Data Bank (PDB) and articles published in peer review journals. |
It complements other existing specialized 3D epitope databases. |
|
BEID |
BEID describes the sequence-structure-function information on immunoglobulin (Ig)-antigen interactions
URL: http://datam.i2r.a-star.edu.sg/BEID |
The current version of the database contains 164 antigens, 126 Ig and 189 Ig-Ag. |
Antigen (Ag) -164
Immunoglobulin (Ig)-126
Ig-Ag complexes-189
Extracted from the Protein Data Bank (PDB). |
Comprehensive structural information of protein and epitope, Rama-chandran plot, Sequence information, Gene Ontology, Visualization tools. Developed for only B-Cell epitope. Not updated from long back. |
|
MPID-T |
MPID-T database is developed for sequence-structure-function information on T cell receptor/peptide/MHC interactions.
URL:http://variome.bic.nus.edu.sg/mpidt/index.html |
It contains all structures of TcR/pMHC and pMHC complexes, with emphasis on the structural characterization of these complexes. |
pMHC - 187
TcR/pMHC - 16
Extracted from the Protein Data Bank (PDB). |
Structural information of protein, Rama-chandran plot, Gene Ontology, Visualization tools, Sequence information Developed for only T-Cell epitope. Not updated from long back. |
|
Epitome |
Epitome is a database of all known antigenic residues and the antibodies that interact with them, including a detailed description of residues involved in the interaction and their sequence / structure environments.
URL: http://www.rostlab.org/services/epitome/ |
It locates the CDRs in the known protein–antibody complexes through the knowledge-based approach |
Ag - 142
Extracted from protein–Ab complex structures |
Structural information of protein, Rama-chandran plot, Gene Ontology, Sequence information, Developed for only B-Cell epitope. Not updated from long back. |
|
IEDB-3D |
IEDB-3D is fully embedded within IEDB, thus allowing structural data, both curated and calculated, and all accompanying information to be queried using multiple search interfaces.
URL: http://www.iedb.org |
IEDB-3D include experiments describing recognition of epitopes or Ag (peptidic or nonpeptidic) by TCRs (T-cell assays describing 3D structures of antigens /epitopes in complexes with MHC and TCR), immunoglobulin or antibodies (B-cell assays describing structures of Ab–Ag complexes), and MHC molecules |
B-Cell - 270
T-Cell -33
MHC -222
Extracted from the Protein Data Bank (PDB) and articles published in peer review journals. |
Structural information of protein. , Rama-chandran plot, Gene Ontology, and the DIMPLOT for the interaction data. |
|
IMGT/3D |
IMGT/3Dstructure-DB provides the closest genes and alleles that are expressed in the AA sequences of the 3D structures, by aligning these sequences with the IMGT domain reference directory.
URL:www.imgt.org/IMGTindex/IMGT3Dstructure-db.html |
IMGT/3Dstructure-DB contains 3D structures of (1) AgR that comprise Ig or Ab and T CR, (2) MHC proteins of class I and class II, (3) peptide/MH (pMH) complexes (pMH1, pMH2), (4) AgR/Ag complexes (IG/Ag, TR/pMH), and (5) related proteins of the immune system (RPI) |
All entries in this database are manually curated from articles published in peer review journals. |
Structural information of protein, Rama- chandran plot, Gene Ontology, Sequence information |
|
CED |
CED has been developed as an information resource for investigators involved in both theoretical and applied immunology research.
URL: http://immunet.cn/ced/ |
CED, provides a collection of conformational epitopes and related information including the residue make up and location of the epitope, the immunological property of the epitope, the source antigen and corresponding antibody of the epitope. |
293 conformational epitopes. All entries in this database are manually curated from articles published in peer review journals. |
Structural information of protein, Rama-chandran plot, Gene Ontology.
Not updated from long back. |
