Figure 1: Schematic representation for transcriptomic studies in TBM coinfected with HIV. RNA was isolated from brain tissue of TBM co-infected with HIV cases and from control samples. Processed the sample further based on the Integrity of the isolated RNA and single colour labeling used and hybridized on 4x44 K arrays. Data was analyzed using GeneSpring GX software and confirmed the selected molecules expression by IHC validation.