IL-1Ra_human Number of residues in favored region 165 (94.3%) Number of residues in allowed region 7 (4.0%) Number of residues in outlier region 3 (1.7%) IL-1Ra_rat Number of residues in favored region 138 (78.4%) Number of residues in allowed region 17 (9.7%) Number of residues in outlier region 21 (11.9%)

Table 1: Ramachandran Plot calculations for 3D model of IL-1Ra in human and rat. All values were computed with PROCHECK program.