Figure 2: Hierarchical cluster of significantly differentiating proteins: An unsupervised cluster of both FFPE biopsies and significant proteins shows clear separation among Benign (BS), Primary Melanoma (PM), and metastatic Melanoma (M) patients. A sub-cluster of proteins shows increased expression in the primary samples compared with both benign and metastatic (in brackets). Red data points indicate increased protein expression, while green indicates decreased expression.