Figure 4: Representative urine protein profiles of m/z values versus peak intensity in the 3000-8000 Da range of one volunteer 6 h after the first LPS gift (b; panel A), showing four discriminative peak intensities 3950 m/z, 4445 m/z, 6723 m/z and 7735 m/z, which correlated significantly to the increase in serum creatinine levels of 5 volunteers (panel B). Maximum levels of serum creatinine were found on day, 3 and data is tested for significance by use of Graphpad Prism 4, and expressed as R2 values.