Parameters |
EAC control |
100 mg/kg salicin |
200 mg/kg
salicin |
5-FU |
Tumor volume (ml) |
3.15a |
1.68c |
0.99e |
0.47f |
Tumor weight (g) |
3.81a |
1.52b |
0.89c |
0.42f |
MST (days) |
22 |
34 |
40 |
43 |
%ILS |
0.0 |
54.54 |
81.81 |
95.45 |
Viable cell count |
7.9×107a |
3.1×107b |
1.3×107d |
0.9×107e |
Nonviable cell count |
0.8×107e |
1.9×107d |
2.8×107b |
3.4×107a |
Total cell count |
8.4×107 |
5.0 ×107 |
4.1×107 |
4.3×107 |
|
Each point represents the mean (n=10 mice per groups).
*The values marked with the different letters show significant difference (Duncan’s multiple range test, P<0.05). |
Table 5: Effect of the isolated salicin compound from leaves of D. gangeticum on tumor volume, tumor weight, mean survival time (MST), percentage increase life span
(%ILS), viable and nonviable, tumor cell count in EAC bearing mice. |