Parameters EAC control 100 mg/kg salicin 200 mg/kg salicin 5-FU
Tumor volume (ml) 3.15a 1.68c 0.99e 0.47f
Tumor weight (g) 3.81a 1.52b 0.89c 0.42f
MST (days) 22 34 40 43
%ILS 0.0 54.54 81.81 95.45
Viable cell count 7.9×107a 3.1×107b 1.3×107d 0.9×107e
Nonviable cell count 0.8×107e 1.9×107d 2.8×107b 3.4×107a
Total cell count 8.4×107 5.0 ×107 4.1×107 4.3×107
Each point represents the mean (n=10 mice per groups).
*The values marked with the different letters show significant difference (Duncan’s multiple range test, P<0.05).
Table 5: Effect of the isolated salicin compound from leaves of D. gangeticum on tumor volume, tumor weight, mean survival time (MST), percentage increase life span (%ILS), viable and nonviable, tumor cell count in EAC bearing mice.