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Figure 3: Hierarchical clustering of the 37 differential protein spots selected using the experimentally-based marker selections method. The spot maps are displayed in columns and the protein spots by rows. Differential expression is shown by color, with the red boxes being upregulated and the green being down-regulated relative to the pooled standard. The clustering fails to group the 0mM Ca2+ (light blue) and 4mM Ca2+ (dark blue) growth conditions for the NYC strain together, which differs from the clustering seen with the entire Base Set (see Figure 2) and the pattern-based method (Figure 4). |