Spot no. Protein name Acc. No.a Theor. MW/pIb Observed MW/pI Queries Matched Mowse score Matching peptide sequences c
2 PCDH8_HUMAN, Protocadherin-8 O95206 112.9/5.35 32.38/5.01 3 40 (R) LVHVEVEVRDVNDHAPR (F)
(R) IAEYNLTLVAEDRGAPPLR (T)
(K) KDLINHMQSGLWACTAECK (I)
5 BMAL2_HUMAN, Aryl hydrocarbon receptor nuclear translocator-like protein 2 Q8WYA1 70.8/7.01 35.46/5.19 3 45 (R) SWPPNIVGMEEER (N)
(R) LQSSSYLDDSSPTGLMK (D)
(K) ELFPPSPSEMGELEATR (Q)
13 ALBU_HUMAN, Serum albumin P02768 69.3/5.92 34.79/5.38 1 32 (K) KVPQVSTPTLVEVSR (N)
16 ALBU_HUMAN, Serum albumin P02768 69.3/5.92 64.3/5.46 1 36 (R) RHPDYSVVLLLR (L)
17 ALBU_HUMAN, Serum albumin P02768 69.3/5.92 64.29/5.60 4 79 (R) RHPDYSVVLLLR (L)
(K) KVPQVSTPTLVEVSR (N)
(R) RHPYFYAPELLFFAK (R)
(K) VFDEFKPLVEEPQNLIK (Q)
18 PGBM_HUMAN, Basement membrane- specific heparan sulfate proteoglycan core protein (Endorepellin; the C-terminal domain V of perlecan) P98160 468.5 / 6.06 23.96/5.93 1 60 (R) SLPEVPETIELEVR (T)
24 ALBU_HUMAN, Serum albumin P02768 69.3/5.92 62.78/5.92 3 70 (R) RHPDYSVVLLLR (L)
(K) KVPQVSTPTLVEVSR (N)
(R) RHPYFYAPELLFFAK (R)
a) Accession number according to SwissProt database
b) pI and MW values are calculated by the MASCOT software
c) Matching peptide sequences and percentage of amino acid sequence coverage are given by MASCOT for the identified protein
Table 2: Protein annotation of candidate protein markers in cervical cancer urine based on the SwissProt database.