Figure 6: Distribution of intensities for 8 arrays of benchmark sera before and after normalization. The distributions are presented as sorted medium summarized intensities across all glycans which have survived the screening of low intensity and low ICC glycans. In order to emphasize the differences, the diagram shows only 35 glycans which correspond to highest intensities, however similar differences can be observed with all other glycans. The upper diagram confirms the finding in figures 4 and 5 about the inter-array bias. The lower diagram shows the distributions after intra-array normalization. The quantile normalization as much stronger than inter-array normalization (not shown here) would make distributions of all subjects the same and equal to the mean value (represented by the black dotted line in both diagrams).