Figure 8: Intra-class Correlation Coefficient (ICC, black line) estimated for the entire PGA library. There are two ICC curves: the traditional (black curve) and the robust ICC (blue curve), the latter is based on the medians and median absolute deviations as opposed to means and standard deviations. The traditional ICC values are sorted by descending values of ICC, while all other curves in figure are rearranged to reflect the same glycan ordering. As shown, 198 glycans have an ICC value greater than 90%. The diagram also shows the rearranged coefficient of variations: the traditional CV (CD-std, green) and the robust version of CV (CV-mad, magenta). The relatively high ICC values for most of the glycans, as well as the low CV values assure that data in the Nickel Exposure Study qualify for further discriminatory analysis as far as the technical noise is concerned.