Figure 4:Hierarchical clustering of differentially abundant proteins in HaCaT keratinocytes exposed to arsenic.

Clustered heat map of the173 proteins with significant changes in abundance between arsenic treated (AR1, AR2, AR3) and untreated HaCaT cells (C1,C2,C3) as determined by t-test (p<0.05). An unsupervised cluster of significant proteins indicates a difference between the arsenic treated cells and the control cells. Red data points indicate increase protein abundance, while blue indicates decreaseabundance.