Figure 7: Hierarchical cluster plot for the Malovannaya SOI. Two large and two small clusters are visible, shown by the thick green squares. MED appears as separate cluster while INT and POL appear together as dense subsets of one cluster. This is due to the fact that POL and INT can build a more stable aggregation together than POL and MED. The proteins POLR2 A/B/C/G (enframed in yellow) are important interactors within both the POL-INT and the POL-MED aggregation. ELL2 and SPEN (enframed in cyan) are important for the interaction between.