Genename Protein name Molecularweight (kDa) Score Queriesmatched % protein Band ACTB Actin, cytoplasmic 1 41.710 210 13 48 7 ACTG Actin, cytoplasmic 2 41.766 293 34 71 6 ARP2 Actin-related protein 2 44.705 48 2 5 6   Actin-related protein 2/3           ARPC2 complex subunit 2 34.370 172 6 29 8   Actin-related protein 2/3           ARPC5 complex subunit 5 16.810 62 2 20 10 ARP3 Actin-related protein 3 43.327 108 6 17 5 ANXA2 Annexin A2 38.654 289 13 44 6 CAV1 Caveolin-1 20.539 45 2 10 9 CD63 CD63 antigen 25.681 40 2 7 9 CD81 CD81 antigen 25.871 34 2 3 9 CD9 CD9 antigen 25.198 78 3 9 9   Cell division control           CDC42 protein 42 homolog 21.245 60 2 15 10 EZRI Ezrin 69.348 223 16 22 3 ITA1 Integrin alpha-1 130.726 303 13 14 1 ITB1 Integrin beta-1 88.436 136 11 15 2 ICAM1 Intercellular adhesion molecule 1 60.104 213 10 15 4 MOES Moesin 67.697 379 26 33 3 RAC1 Ras-related C3 botulinum toxin substrate 1 21.436 51 3 11 9 RHOA Transforming protein RhoA 21.768 73 4 34 9 VCAM1 Vascular cell adhesion protein 1 81.194 142 9 12 2

Table 1: Identified proteins in MPs isolated from vascular smooth muscle cells treated with lysoPC. Selection of the most relevant proteins identified, indicating the molecular weight, score, number of queries matched, the percentage of the identified protein, and the band where the proteins were identified.