PDB Code Model Length Identity (%) Aminoacid Overlap z-Score Protein Name 1hzhH X-ray 2.70A˚ 457 85.8 452 1919.2 Crystal structure of the intact human IgG b12 with broad and activity against primary HIV=1 isolates 1za6(A) X-ray 2.80A˚ 220 88.6 219 961.0 The structure of an antitumor cha21-domain- deleted huamanized antibody 1hzh(H) X-ray 2.70A˚ 457 85.4 403 1706.0 Crystal structure of the intact human IgG b12 with broad and activity against primary HIV=1 isolates 4d9r(L) X-ray 2.42A˚ 214 61.2 206 618.7 Inhibiting alternative pathway complement activation by targ exosite on factor d

Table 6: PROCHECK Analyses: Stereochemical quality assessment of the predicted protein structures was performed by using PROCHECK program. The analyses confirmed high quality of the protein structures in stereochemistry.