| Spot ID |
MS job run and PI-number |
Protein identified by LC- MS analysis |
Expression and fold change |
P value versus fertile group |
Mol. Wt. and pI |
Moscot
score |
Matched peptide |
Coverage
(%) |
Biological function |
Existing information |
Reference |
| 0 |
111207 - 2626A |
ATP synthase subunit d |
Down (1.51 fold) |
p<0.05 |
18.4 kDa,
5.21 |
206 |
11 |
65 |
Mitochondrial ATP generation |
Down-regulated in endometriosis |
[30] |
| 3 |
111207 - 2626B |
Triose phosphate isomerase |
Up
(1.56 fold) |
p<0.05 |
26.6 kDa,
7.36 |
635 |
39 |
- |
Glucose metabolism |
Secreted in uterine fluid of early and mid-secretary endometrium of fertile women |
[28] |
| 4 |
111207 - 2626C |
Heat shock protein beta-1 |
Up
(1.61 fold) |
p<0.05 |
22.7 kDa,
5.98 |
317 |
21 |
49 |
Molecular chaperone |
Altered secretion in uterine fluid from early to mid-secretory endometrium of fertile women
Increased expression in mid-secretory phase as compared to mid-proliferative phase endometrium of fertile women
Down regulated mRNA expression during the window of implantation |
[28]
[29]
[27] |
| 5 |
111207 - 2626D |
Cold agglutinin FS-2 L-chain (Fragment) |
Down
(1.53 fold) |
p<0.05 |
25.7 kDa,
5.94 |
147 |
18 |
- |
Blood agglutination |
- |
|
| 6 |
111207 - 2626E |
Apolipoprotein A1 |
Up
(2.67 fold) |
p<0.01 |
30.7 kDa,
5.56 |
793 |
71 |
78 |
Lipid metabolism |
Up-regulated in the endometrium of RIF patients
Down-regulated in uterine lavage in women with unexplained infertility |
[8]
[9] |
| 8 |
111207 - 2626F |
cDNA FLJ60461, highly similar to Peroxiredoxin-2 |
Up
(1.53 fold) |
p<0.05 |
20.0 kDa, 8.90 |
209 |
15 |
49 |
Antioxidant
system |
Down-regulated in endometriosis
Decreased secretion in the uterine fluid from early to mid-secretory endometrium of fertile women |
[30]
[28] |
| 11 |
111207 - 2626G |
Uncharacterized protein |
Down
(1.50 fold) |
p<0.05 |
22.7 kDa, 8.51 |
95 |
5 |
20 |
- |
- |
|
| 13 |
111207 – 2626H |
cDNA clone BRAMY2012536, highly similar to Homo sapiens asparaginase like 1 mRNA |
Up
(1.57 fold) |
p<0.05 |
32.0 kDa,
5.75 |
108 |
4 |
16 |
Amino acid metabolism |
- |
|
| 15 |
111207 – 2626I |
cDNA, FLJ96792, highly similar to Homo sapiens calmodulin 2 (CALM2),mRNA |
Up
(1.55 fold) |
p<0.01 |
16.7 kDa, 4.09 |
99 |
5 |
41 |
Ca +2 signaling |
- |
|
| 18 |
111207 – 2626J |
Hemoglobin subunit beta |
Up
(1.76 fold) |
p<0.05 |
16.0 kDa,
6.75 |
528 |
41 |
74 |
Oxygen transport |
Less secretion in the uterine fluid from early to mid-secretory endometrium of fertile women |
[28] |
| 19 |
111207 – 2626K |
IGK@ protein |
Up
(2.07 fold) |
p<0.01 |
26.0 kDa,
5.94 |
187 |
11 |
22 |
Immune system |
Decreased secretion in the uterine fluid from early to mid-secretory endometrium of fertile women |
[28] |
| 23 |
111207 – 2626L |
60S acidic ribosomal protein P2 |
Down
(2.21 fold) |
p<0.01 |
11.6 kDa, 4.42 |
150 |
5 |
60 |
Protein synthesis |
- |
|
