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Figure 6: Binding pose of the MTX04 in DHFR domain. The 2D (left side with white background) and 3D (right side with black background) views of MTX04 docked in DHFR domain. In 2D, the dotted arrows are showing potential hydrogen bonds with Asp54, Arg59, Ser120, Arg122 and Leu164. In 3D, the MTX04 is in green color while the active site residues are in element style. |