Figure 8: Docking poses of the MTX04 in PfDHFR and hDHFR. The 3D view of the conformation of MTX04 in (a) DHFR domain of PfDHFR-TS and (b) hDHFR protein. Surface potential around ligand was calculated by Discovery Studio Tools. The residues with hydrogen bond donating potential and hydrogen bond accepting potential are in purple and green color respectively.