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Figure 2: Carbohydrate microarrays identify tumor-associated oligomannosyl antigens that differ from the 2G12-specific HIV-1 carbohydrates by the Man9-cluster configuration. Panel A illustrates the structures of three Man9-conjugates: 1) M9(2G12), 2) Man9-KLH, and 3) Man9-BSA. The glycan-binding activities of antibodies are shown as the mean fluorescent intensities of triplicate detections of each antigen with red and blue column for TM10 and 2G12, respectively. Each error bar is constructed using 1 standard deviation from the mean. |