Biological processes Nom Ros Nim Nef Bus Glaf
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 27 23 13 10 28 2
organic acid metabolic process 26 19 6 9 10 5
transport 13 13 7 6 11 5
carbohydrate metabolic process 12 7 6 3 8 3
metabolic process 7 4 2 3 5  
alcohol metabolic process 7 2 1 2    
protein modification process 6 3 3 3 4 2
proteolysis 5 2 2 4 4  
protein folding 5 3 4   1  
lipid metabolic process 4 3 2   2 1
protein complex assembly 3 3 4 1 2 2
cell morphogenesis 3 3 3 4   2
RNA splicing, via transesterification reactions 3     3 8  
immune system process 3 3 1 4 1  
generation of precursor metabolites and energy 2 6   6 12  
translation 1 3 4 5 6 1
system process   2 3 2 4 4
chromatin organization   1 4 1 5 1
Table showing the number of protein changes observed when HepG2 cells were treated with the respective compounds at 10 μM drug concentration for 48 hrs at 37°C. The numbers in the table represent the number of proteins that changed significantly for each biological process following drug treatment.
Table 1: Gene Ontology Analysis of Protein Changes in Compound Treated Cells.