Nimesulide 3µM 48hrs Buspirone 3µM 48hrs
MeSH Term p-value MeSH Term p-value
Oxidative Stress 1.55E-12 Cell Hypoxia 3.44E-26
Gene Expression Regulation, Neoplastic 6.70E-07 Anoxia 1.30E-14
Pulmonary Disease, Chronic Obstructive 2.04E-06 Lipid Metabolism 1.40E-13
Liver Neoplasms 2.37E-06 Gene Expression Regulation, Enzymologic 2.43E-08
Carcinoma, Hepatocellular 2.48E-06 Gene Expression Regulation, Neoplastic 3.15E-07
Lipid Metabolism 8.36E-05 Glycolysis 1.17E-06
Emphysema 1.05E-04 Fasting 3.54E-05
Metabolic Detoxication, Phase II 3.13E-04 Genes, myc 8.53E-05
Gene Expression Regulation, Enzymologic 3.24E-04 Osmotic Pressure 1.03E-04
Oxidation-Reduction 6.61E-04 Oxidation-Reduction 2.08E-04
Organ Size 9.24E-04 Adaptation, Physiological 4.17E-04
The MeSH term enrichment analysis provides the biological context of the evidence supporting the CRE molecular hypotheses. The p-values are computed by Fisher’s exact test.
Table 2: MeSH Terms enriched for the CRE hypotheses.