Sc Om
Actin cytoskeleton Protein S100-A11 (-3.51) Unconventional myosin-1c (-6.36)
Protein cordon-bleu (-1.65)a Girdin (-4.85)
Moesin (1.93) Rho GTPase-activating protein 4 (-2.99)
Myosin-9 (2.11) Elongation factor 1-alpha 2 (-2.91)
CD99 antigen (-2.73)
TNS 1 protein (-2.68)
  Serum deprivation-response protein (2.50)
  Protein cordon-bleu (-2.07)
  A-kinase anchor protein 12 (-1.96)
  Caldesmon (-1.96)
  Annexin A1 (1.54)
  Moesin (2.03)
Lipid metabolism Moesin (1.93) Diazepam binding inhibitor (-3.53)
  Apolipoprotein A-IV (-1.90)
  Gamma-synuclein (-1.83)
  Annexin A1 (1.54)
  Serotransferrin (1.72)
  Moesin (2.03)
  Ceruloplasmin (2.65)
Oxidative stress Protein S100-B (2.83) Afamin (-1.94)
  Apolipoprotein A-IV (-1.90)
  Serotransferrin (1.72)
  Ceruloplasmin (2.65)
Cell signaling   Girdin (-4.85)
  A-kinase anchor protein 12 (-1.96)
  Decorin (11.73)
Mitochondrial function Cytochrome c oxidase   subunit 6B1 (-4.03) Cytochrome c oxidase subunit 6B1 (-7.27)
Stromal cell-derived factor 1 (4.09) 10 kDa heat shock protein (-2.72)
ATP synthase-coupling factor 6 (-2.44)
  Ryanodine receptor 2 (3.85)
ER stress 78 kDa glucose- regulated protein (2.55) 78 kDa glucose-regulated protein (7.09)
*p value < 0.05 is significant
Table 4: Differentially abundantproteins in diabetic and nondiabetic patients by biological and metabolic processes