CV ACCb SEN SPC PPV     NPV 1 0.706 0.75 0.667 0.667 0.75 2 0.706 0.75 0.667 0.667 0.75 3 0.706 0.75 0.667 0.667 0.75 4 0.706 0.75 0.667 0.667 0.75 5 0.824 0.875 0.778 0.778 0.875 6 0.765 0.75 0.778 0.75 0.778 7 0.647 0.625 0.667 0.625 0.667 8 0.706 0.75 0.667 0.667 0.75 9 0.706 0.75 0.667 0.667 0.75 10 0.812 0.75 0.75 0.857 0.778 11 0.765 0.75 0.778 0.75 0.778 12 0.765 0.75 0.778 0.75 0.778 13 0.765 0.75 0.778 0.75 0.778 14 0.765 0.75 0.778 0.75 0.778 15 0.765 0.75 0.778 0.75 0.778 16 0.882 0.875 0.889 0.875 0.889 17 0.765 0.75 0.778 0.75 0.778 18 0.765 0.75 0.778 0.75 0.778 19 0.706 0.625 0.778 0.714 0.7 20 0.588 0.5 0.667 0.571 0.6 AVG 0.741 0.738 0.744 0.721 0.762 SD 0.064 0.08 0.072 0.073 0.061 MOE 0.03 0.037 0.034 0.034 0.029 aResults of twenty 10-fold cross-validations. Class 1, GM grade 0: 9 subjects; class 2, GM grade 1 or 2: 8 subjects. bACC, SEN, SPC, PPV, NPV are defined in Methods. AVG, SD and MOE are the average, standard deviation and 95% margin of error of each performance measure over the 20 CVs.

Table 1: Prediction of occurrence of radiation-induced gastrointestinal mucositis based on pre-radiation protein profiles.a