ADMA SDMA NMMA Citrulline Arginine ADMA Pearson Correlation 1 .549** .290 .124 .361 Sig. (2-tailed)   .008 .190 .582 .099 SDMA Pearson Correlation .549** 1 .017 .158 .073 Sig. (2-tailed) .008   .942 .482 .748 NMMA Pearson Correlation .290 .017 1 .106 .338 Sig. (2-tailed) .190 .942   .640 .123 Citrulline Pearson Correlation .124 .158 .106 1 .449* Sig. (2-tailed) .582 .482 .640   .036 Arginine Pearson Correlation .361 .073 .338 .449* 1 Sig. (2-tailed) .099 .748 .123 .036   **. Correlation is significant at the 0.01 level (2-tailed). *. Correlation is significant at the 0.05 level (2-tailed).

Table 3: Pearson Correlation matrix of the arginine metabolite levels of both CKD and control mice (n=11/ group; total =22).