A: Interaction proteins associated with NPM1
| Upstream Regulator |
p-value of overlap |
Molecule Type |
Target molecules in dataset |
| MYC |
5.78E-06 |
transcription regulator |
CAPZB,LDHA,PHB,PHB2,PPIA,RBBP4,VDAC2 |
| MYCN |
1.59E-03 |
transcription regulator |
LDHA,PHB,RBBP4 |
| ALX3 |
2.02E-03 |
transcription regulator |
GFAP |
| E2F1 |
4.68E-03 |
transcription regulator |
HNRNPK,PHB,RBBP4 |
| OLIG2 |
5.06E-03 |
transcription regulator |
GFAP |
| MYCBP |
7.07E-03 |
transcription regulator |
LDHA |
| Pdx1 |
8.08E-03 |
transcription regulator |
GFAP |
| HNF4A |
1.07E-02 |
transcription regulator |
MYL6,PHB,PHB2,RBBP4,VDAC1,VDAC2 |
| PURA |
1.41E-02 |
transcription regulator |
GFAP |
| KCNIP3 |
1.51E-02 |
transcription regulator |
GFAP |
| NFIX |
1.81E-02 |
transcription regulator |
GFAP |
| SUPT16H |
2.11E-02 |
transcription regulator |
HNRNPK |
| NR2E1 |
2.21E-02 |
ligand-dependent nuclear receptor |
GFAP |
| HDAC4 |
2.60E-02 |
transcription regulator |
LDHA |
| Nuclear factor 1 |
2.90E-02 |
group |
GFAP |
| HIF1A |
3.50E-02 |
transcription regulator |
LDHA,PPIA |
| NRF1 |
4.37E-02 |
transcription regulator |
VDAC1 |
| E2F6 |
4.46E-02 |
transcription regulator |
RBBP4 |
© 2000-2013 Ingenuity Systems, Inc. All rights reserved. |
B: Proteins regulated by NPM1
| Upstream Regulator |
p-value of overlap |
Molecule Type |
Target molecules in dataset |
| MYCN |
3.28E-05 |
transcription regulator |
CAD,LDHA,NPM1,PDIA4,RPL11,RPL4 |
| MYC |
1.39E-04 |
transcription regulator |
ANXA6,CAD,DBN1,GSR,LDHA,MCM5,NPM1,ROCK2,TFRC |
| MYCBP |
1.42E-04 |
transcription regulator |
CAD,LDHA |
| NFE2L2 |
4.15E-04 |
transcription regulator |
CBR1 (includes EG:100360507),GSR,PDIA4,PPIB,PSMD3,UBE2K |
| TP53 |
9.16E-04 |
transcription regulator |
AK1,ANXA6,GSR,LDHA,MCM2,MCM5,NPM1,PARK7,PSMD3,STAT1 |
| Meg3 |
1.05E-02 |
transcription regulator |
IQGAP1 |
| E2F2 |
1.13E-02 |
transcription regulator |
MCM2,MCM5 |
| RBL1 |
1.27E-02 |
transcription regulator |
MCM2,MCM5 |
| XBP1 |
1.28E-02 |
transcription regulator |
PDIA4,PPIB,SRPRB |
| GTF2H4 |
1.31E-02 |
transcription regulator |
CAD |
| MYCL1 |
1.31E-02 |
transcription regulator |
CAD |
| CDKN2A |
1.49E-02 |
transcription regulator |
AK1,MCM5,NPM1 |
| E2F3 |
1.51E-02 |
transcription regulator |
MCM2,MCM5 |
| TBX2 |
1.67E-02 |
transcription regulator |
MCM2,MCM5 |
| MAX |
1.80E-02 |
transcription regulator |
CAD,NPM1 |
| TLE1 |
1.83E-02 |
transcription regulator |
ROCK2 |
| ERG |
2.45E-02 |
transcription regulator |
DBN1,ROCK2 |
| KDM5A |
2.86E-02 |
transcription regulator |
MCM2 |
| CCNT1 |
2.86E-02 |
transcription regulator |
CAD |
| ZNF148 |
3.12E-02 |
transcription regulator |
STAT1 |
| E2f |
3.40E-02 |
group |
MCM2,MCM5 |
| HTT |
3.57E-02 |
transcription regulator |
CBR1 (includes EG:100360507),GSR,LDHA,PSMD3,TFRC |
| MXI1 |
3.63E-02 |
transcription regulator |
LARS |
| HR |
3.88E-02 |
transcription regulator |
HNRNPC |
| GTF2I |
3.88E-02 |
transcription regulator |
PDIA4 |
| Cyclin E |
4.13E-02 |
group |
ROCK2 |
| HIF1A |
4.19E-02 |
transcription regulator |
LDHA,NPM1,TFRC |
| SP100 |
4.39E-02 |
transcription regulator |
HSPA6 |
| NR1D1 |
4.39E-02 |
ligand-dependent nuclear receptor |
STAT1 |
| IRF7 |
4.42E-02 |
transcription regulator |
PSME2,STAT1 |
| FOXO3 |
4.42E-02 |
transcription regulator |
CAD,LARS |
| KLF2 |
4.73E-02 |
transcription regulator |
STAT1,TFRC |
| BRCA1 |
4.73E-02 |
transcription regulator |
AK1,STAT1 |
© 2000-2013 Ingenuity Systems, Inc. All rights reserved. |
