Figure 4: Ingenuity Pathway Analysis of metabolites that differed significantly between GBM groups compared to control (untreated healthy) after a Welch’s twosample t-test analysis. The top network has shown here. This network has the metabolites that were over-expressed in the samples from patients with GBM highlighted in red, and the under expressed metabolites highlighted in green. AKt was identified as a major hub molecule, with direct/indirect interactions with metabolites.