Figure 5: Schematic representation of derived pathways associated with renal clear cell carcinoma. The networks of these identified proteins mapped to canonical pathways from the Ingenuity Pathways Analysis (IPA, Ingenuity Systems) library were used to compare up-regulated (A) or downregulated (B) protein molecules between normal and diseased tissues. Identified proteins with up- and down-regulation are displayed in green and red, respectively and have different shapes to indicate different functions associated with metastasis, tumor growth, invasion and angiogenesis. The gray arrows indicate the biological interrelationships between molecules.