Application |
Type of Assay |
Sample / Co-Factor |
Array Platform |
Reference |
RNA-binding proteins |
Protein-RNA interaction |
Fluorescently labelled total or mRNA |
Yeast proteome array |
[67] |
DNA-binding proteins |
Protein-DNA interactions |
Fluorescently labelled DNA oligonucleotides |
Human protein microarray |
[134] |
Kinase substrate identification |
Protein phosphorylation |
Radioactive ATP |
Yeast protein microarray |
[28] |
Protein kinase activity |
Enzyme kinetics |
Radioactive ATP |
Peptide microarray |
[77] |
Protein-protein interaction quantification |
Protein-protein interactions |
Labelled peptides |
Protein domain microarray |
[84] |
Posttranslational modification |
Protein sumoylation |
Antibodies |
Protein microarray |
[24] |
Interactome analysis |
Protein-protein interaction |
Antibodies |
Human protein array |
[6] |
Host-pathogen interactions |
Protein-protein interaction |
Antibodies |
Human protein microarray |
[27] |
Biomarker discovery |
Protein-protein interactions |
Antibodies |
E. coli proteome chip |
[79] |
Drug discovery |
Protein-small molecule interaction |
Labelled ligands |
Yeast proteome |
[88] |