| Application |
Type of Assay |
Sample / Co-Factor |
Array Platform |
Reference |
| RNA-binding proteins |
Protein-RNA interaction |
Fluorescently labelled total or mRNA |
Yeast proteome array |
[67] |
| DNA-binding proteins |
Protein-DNA interactions |
Fluorescently labelled DNA oligonucleotides |
Human protein microarray |
[134] |
| Kinase substrate identification |
Protein phosphorylation |
Radioactive ATP |
Yeast protein microarray |
[28] |
| Protein kinase activity |
Enzyme kinetics |
Radioactive ATP |
Peptide microarray |
[77] |
| Protein-protein interaction quantification |
Protein-protein interactions |
Labelled peptides |
Protein domain microarray |
[84] |
| Posttranslational modification |
Protein sumoylation |
Antibodies |
Protein microarray |
[24] |
| Interactome analysis |
Protein-protein interaction |
Antibodies |
Human protein array |
[6] |
| Host-pathogen interactions |
Protein-protein interaction |
Antibodies |
Human protein microarray |
[27] |
| Biomarker discovery |
Protein-protein interactions |
Antibodies |
E. coli proteome chip |
[79] |
| Drug discovery |
Protein-small molecule interaction |
Labelled ligands |
Yeast proteome |
[88] |