The data set RMSE ABS Fold 1 of the training data 0.2057 0.1678 Fold 2 of the training data 0.1516 0.1238 Fold 3 of the training data 0.1746 0.1393 Fold 4 of the training data 0.1538 0.1226 Fold 5 of the training data 0.1677 0.1383 Fold 6 of the training data 0.1692 0.1348 Fold 7 of the training data 0.1900 0.1487 Fold 8 of the training data 0.2330 0.1873 Fold 9 of the training data 0.2287 0.1939 Fold 10 of the training data 0.1721 0.1377 Test data 0.1764 0.1423

Table 3: The RMSE and ABS of the trained multiple sequence alignment based SVM with the best parameter set on each fold of the training data as well as the test data set.