Family NRPred-FS iNR-PhysChem NR-2L ACC MCC ACC MCC ACC MCC NR 0.97 0.95 0.83 Non-NR 0.97 0.95 0.83 Overall 0.98 0.96 0.85

Table 4: Comparison of the prediction results among NRPred-FS, iNR-PhysChem and NR-2L in identifying NRs and non-NRs by the LOOCV on the old dataset.