Accession Number Codon change Amino acid change Codon number Phenotype CM980233 gTTT-CTT Phe-Leu 32 Breast cancer CM970178 TAT-TGT Tyr-Cys 42 Breast cancer CM014326 tGAA-TAA Glu-Term 45 Breast cancer CM011914 aGAA-TAA Glu-Term 49 Breast cancer CM980234 AAA-AGA Lys-Arg 53 Breast cancer CM041729 ACT-ATT Thr-Ile 64 Breast cancer CM980235 aTTC-CTC Phe-Leu 81 Breast cancer CM040380 TTA-TGA Leu-Term 105 Breast cancer CM021250 ATG-ACG Met-Thr 192 Pancreatic cancer CM960192 TGG-TAG Trp-Term 194 Breast cancer CM980236 CCA-CGA Pro-Arg 201 Breast cancer CM980237 GTC-GCC Val-Ala 211 Breast cancer CM980238 tCCT-TCT Pro-Ser 222 Breast cancer CM042309 tACT-GCT Thr-Ala 225 Breast cancer CM032200 TCA-TAA Ser-Term 273 Breast cancer CM984124 aCAA-TAA Gln-Term 321 Breast cancer CM994736 AGCa-AGA Ser-Arg 326 Breast cancer CM994284 cAAG-GAG Lys-Glu 327 Breast cancer CM002750 aAAT-CAT Asn-His 372 Breast cancer CM021509 cAAG-TAG Lys-Term 385 Breast cancer CM970179 TTG-TAG Leu-Term 414 Breast cancer CM004188 GAA-GGA Glu-Gly 462 Breast cancer CM021955 tAAG-TAG Lys-Term 467 Breast cancer CM010167 ATA-ACA Ile-Thr 505 Breast cancer CM980239 TGTc-TGG Cys-Trp 554 Breast cancer, male CM043454 TTA-TGA Leu-Term 557 Breast cancer CM043977 TGGc-TGA Trp-Term 563 Breast cancer CM033756 cACT-CCT Thr-Pro 582 Breast cancer CM043978 TCA-TAA Ser-Term 611 Breast cancer CM004714 ATAa-ATG Ile-Met 729 Breast cancer CM042681 cATG-GTG Met-Val 784 Breast cancer CM994285 tGAT-AAT Asp-Asn 935 Breast cancer CM970180 tAAA-TAA Lys-Term 944 Breast cancer CM040688 gAAG-TAG Lys-Term 1026 Breast cancer CM043979 TTA-TGA Leu-Term 1053 Breast  cancer CM020102 TCA-TGA Ser-Term 1099 Breast cancer

Table 1: List of Mutations and its corresponding disease Pheno-type collected from HGMDMaterials