PCSa ESCAb
   

PLGA502Hc  Surfactant (Pluronic)c

Sample Sized (nm) PDI d,e z-pot (mV)d C OO (1)f
290.5 eV
COO–C–O (2)f
288.5 eV
C –CH (3)f (overlapped to (4)f)
286.5 eV
PLGA502H NPs 171 (11) 0.09 (0.01) −31 (2) 30.8 35.9 33.3
Neu5Ac-PLGA502 NPs 163 (5) 0.20 (0.02) −37 (4) 36.0 35.4 28.6
aPCS: Photon Correlation Spectroscopy analyses
bESCA: Electron Spectroscopy for Chemical Analysis
cAtomic composition and numbering of the components of PLGA502H NPs, PLGA and Pluronic.
dThe values represent the means of at least three experiments; standard deviation in parentheses.
ePDI: polydispersity index.
fThe numbers indicate the carbon atom type
Table 1: Chemico-physical characterization and ESCA analysis of PLGA502H NPs and Neu5Ac-PLGA502 NPs