Figure 3: Optimized transition state geometry for the aquation of A) Cisplatin from gas-phase: Pt(NH3)2Cl2(OH2) (1a). B) BNP3029 from gas-phase: Pt[N≡C(CH2)3(C6H5)]2Cl2(OH2) (3a). All distances are in Angstroms (Å) and angles are in degrees. C) Cisplatin from solution-phase: Pt(NH3)2Cl2(OH2) (1a).