Studied formulations; doses of 50 µg/mouse Serum IFN titers, log2 (mean±SD) 8 h 24 h 48 h Del-Immune V® 4.0 ± 0.03* 4.4 ± 0.03* 3.41 ± 0.03* Bifidim 3.6 ± 0.01* 4.0 ± 0.03* 2.7 ± 0.03 Control 2.0 ± 0.02 2.0 ± 0.03 2.0 ± 0.03 All values expressed, mean ± SD * p ≤ 0.05 IFN titers presented log2 were calculated by using data from 3 repeated experiments (n=5 per group). Circulating IFN levels were measured through observation period using the cytopathogenic effect inhibition assay.

Table 1: Murine Serum IFN Titers after One-Time Administration of Del-Immune V® or Bifidim.